handicap noun
1 physical/mental disability
ADJ. serious, severe | mild | mental, physical, visual She can't drive because of her visual handicap.
VERB + HANDICAP be born with, have, suffer (from) Over a million people in Great Britain suffer from mental handicap. | cause | cope with, overcome She has managed to overcome her physical handicaps.
PREP. despite a/the ~ Despite her handicap, Jane is able to hold down a full-time job.
2 disadvantage
ADJ. big, considerable, great, major, real, serious, severe, terrible Lack of transport was a major handicap.
VERB + HANDICAP have, suffer If you don't speak the language, you've got a real handicap. | prove His lack of height can prove a handicap against tall players.
PREP. despite a/the ~ | ~ to This could be a serious handicap to her education.
You can also check other dicts: handicap (English, 中文解释 ), wordnet sense, Collins Definition